If allergies, hives or itchy eyes slow you down, the right antihistamine can help fast. This page explains the main types, when to pick each one, common side effects, and simple ways to save when buying them in Mexico.
There are two main groups: first‑generation and second‑generation. First‑generation drugs (diphenhydramine, promethazine) work well but often make you sleepy. Use them if you need help sleeping or for short‑term severe allergic reactions, but avoid driving or operating machines after taking them.
Second‑generation antihistamines (loratadine, cetirizine, fexofenadine) cause little or no drowsiness. These are best for daily allergy control—think hay fever, pet allergies, or chronic sneezing. If you need all‑day relief for work or school, start with a second‑generation option.
Ask yourself: Do I need quick relief or daytime alertness? If the answer is daytime, choose loratadine (Claritin/generic), cetirizine (Zyrtec/generic) or fexofenadine (Allegra/generic). For sudden, severe itching or short naps, diphenhydramine (Benadryl) works but plan for drowsiness.
Special cases: pregnant or breastfeeding? Talk with your doctor—some antihistamines are safer than others. Seniors should avoid first‑generation drugs due to confusion and falls. If you’re on other meds (especially sedatives or certain antidepressants), check interactions with a pharmacist.
In Mexico many antihistamines are available OTC. Brands you’ll see: loratadina, cetirizina, fexofenadina, and diphenhidramina. Generics are common and much cheaper—don’t skip them. Pharmacists in Mexico can often recommend an effective generic with the same active ingredient.
Compare prices across pharmacies and online drugstores. Look at price per tablet or per 30‑day supply, not just the package price. Avoid combo cold medicines unless you need every ingredient—those cost more and can add unwanted side effects.
Buy the correct dose and check the expiration date. For chronic allergies, buying a 30‑ or 90‑day pack usually lowers the per‑pill cost. If you travel, bring a translated note with the generic name (loratadine, cetirizine) to show local pharmacies or customs.
Common safety reminders: don’t mix antihistamines with alcohol or other sedatives, watch for excessive drowsiness, and stop if you get severe side effects like fast heartbeat or rash. When in doubt, ask a pharmacist or seek a quick consult with a local clinician.
Want price comparisons or more product details? Use our site search to find specific drug pages and current Mexican pharmacy prices. If you have questions about a brand or a prescription, contact us and we’ll point you to the right article or resource.
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