Montelukast Side Effects: What You Need to Know Before Taking It
When you take montelukast, a leukotriene receptor antagonist used to prevent asthma and allergy symptoms. Also known as Singulair, it’s often prescribed for kids and adults who need daily control of wheezing, nasal congestion, or exercise-induced breathing trouble. But while it works well for many, it’s not just about blocked airways—some users face side effects that aren’t talked about enough.
One of the most serious concerns linked to montelukast, a leukotriene receptor antagonist used to prevent asthma and allergy symptoms. Also known as Singulair, it’s often prescribed for kids and adults who need daily control of wheezing, nasal congestion, or exercise-induced breathing trouble. is its impact on mental health. The FDA issued a black box warning after reports of depression, anxiety, suicidal thoughts, and even hallucinations in people taking it. These aren’t rare flukes—they show up in real patient stories and clinical reports. If you or someone you care for starts feeling unusually sad, restless, or withdrawn after starting montelukast, don’t wait. Talk to your doctor right away.
More common side effects are easier to miss. Headaches, stomach pain, and nausea happen often enough that some people just think it’s "normal"—but they’re signs your body might not be handling the drug well. Kids on montelukast sometimes get bedwetting or trouble sleeping. Adults report dizziness or a strange taste in the mouth. And while it’s not an antibiotic, montelukast can still mess with your gut. Some users get diarrhea or constipation, and others say they feel more tired than usual.
It’s also worth knowing who shouldn’t take it. If you’ve had a bad reaction to similar asthma drugs before, or if you have liver problems, your doctor might pick something else. And if you’re on other meds—like aspirin, ibuprofen, or even certain antifungals—there could be hidden interactions. Montelukast doesn’t usually cause weight gain or high blood pressure, but it doesn’t play nice with everything.
What you’ll find below are real, practical posts from people who’ve dealt with montelukast side effects firsthand. Some switched to other asthma controllers after problems arose. Others tracked their mood changes and found patterns. One parent noticed her son’s nightmares stopped the moment they stopped the pill. These aren’t just stories—they’re clues that help you make smarter choices.