When you have common variable immunodeficiency, a rare immune disorder where the body doesn’t make enough antibodies to fight infections. Also known as CVID, it leaves people vulnerable to repeated sinus, lung, and gut infections that won’t go away with regular antibiotics. Unlike the flu or a cold, CVID doesn’t clear up on its own. Without the right treatment, those infections can lead to lasting lung damage, digestive problems, or even autoimmune conditions. This isn’t something you can treat with vitamins or supplements alone—it needs targeted medical care.
The core of CVID treatment, a lifelong therapy that replaces missing antibodies to help the body defend itself is immunoglobulin therapy, infusions or injections of purified antibodies from healthy donors. Some people get it every week through an IV, others every few weeks under the skin. It’s not a cure, but it’s the most proven way to prevent serious infections. Not all treatments are equal—some clinics push expensive add-ons like probiotics or herbal immune boosters, but there’s little evidence they help with CVID. Stick to what’s backed by decades of research: antibody replacement, antibiotics for flare-ups, and regular monitoring.
People with CVID often end up in emergency rooms because they mistake a bad infection for something minor. If you’re on immunoglobulin therapy and still getting pneumonia or chronic diarrhea, your dose might need adjusting. Or you might have another condition hiding in plain sight—like autoimmune cytopenia or granulomatous disease—that needs its own treatment. That’s why tracking symptoms and working with an immunologist matters more than any supplement. You’re not just managing infections—you’re protecting your organs from slow, silent damage.
What you won’t find in most online guides is how hard it is to get consistent care. Insurance often fights coverage for infusions. Some pharmacies don’t stock the right brands. And many doctors still don’t know CVID well enough to spot it early. That’s why the posts below give you real, practical advice: how to push back when your treatment is denied, what lab tests actually matter, which antibiotics work best for CVID-related infections, and how to tell if your immune system is holding up—or falling apart.
Below, you’ll find clear, no-fluff guides from people who’ve been there. No marketing. No hype. Just what works, what doesn’t, and how to make sure you’re not left guessing when your next infection hits.
Common Variable Immunodeficiency (CVID) is a serious antibody deficiency that causes frequent infections and long-term health risks. Learn how immunoglobulin therapy works, why diagnosis takes years, and what new treatments are on the horizon.
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