Overdose Signs: How to Recognize and Respond to a Drug Emergency

When someone is having an overdose, a dangerous reaction to taking too much of a drug, often leading to life-threatening symptoms. Also known as drug toxicity, it can happen with prescription meds, street drugs, or even supplements if taken in excess. It’s not always obvious—some people slump over quietly, others gasp or shake. The key is knowing what to look for before it’s too late.

Opioid overdose, a type of overdose caused by drugs like heroin, fentanyl, or prescription painkillers is one of the most common and deadly. Signs include slow or stopped breathing, blue lips or fingernails, unresponsiveness, and pinpoint pupils. But overdoses aren’t just from opioids. Serotonin syndrome, a dangerous buildup of serotonin from mixing certain antidepressants or drugs can cause agitation, high fever, rapid heartbeat, and muscle rigidity. Even stimulants like Adderall or cocaine can trigger overdose signs like chest pain, seizures, or extreme confusion. These aren’t rare events—overdose deaths have risen sharply in the last decade, and many happen because people didn’t recognize the warning signs in time.

You don’t need to be a doctor to act. If someone is unresponsive and not breathing normally, call 911 right away. If you have naloxone, a medication that can reverse an opioid overdose within minutes, use it. It’s safe, easy to use, and available for free in many places. Even if you’re unsure if it’s an opioid overdose, giving naloxone won’t hurt someone who isn’t overdosing on opioids. The real risk is doing nothing.

What you’ll find below are real, practical guides that break down exactly what to watch for with different drugs, how to respond in an emergency, and why some people survive while others don’t. These aren’t theoretical articles—they’re written by people who’ve seen the aftermath, studied the data, and tested what works. Whether you’re worried about a loved one, taking meds yourself, or just want to be prepared, this collection gives you the facts you need to act fast—and maybe save a life.

How to Recognize Overdose from Sedatives and Sleep Medications
Dec, 9 2025

How to Recognize Overdose from Sedatives and Sleep Medications

Learn the critical signs of sedative and sleep medication overdose-unresponsiveness, slow breathing, blue lips-and what to do immediately to save a life. No waiting. No guessing.